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: A total of patients were included in the intent-to-treat analysis; patients received granisetron and patients received prochlorperazine.

Gruben sex To demonstrate the efficacy of oral granisetron 1 mg twice daily for the prevention of late onset nausea and vomiting after moderately emetogenic chemotherapy that includes cyclophosphamide, carboplatin, or doxorubicin. Abstract Purpose: To demonstrate the efficacy of oral granisetron 1 mg twice daily for the prevention of late onset nausea and vomiting after moderately emetogenic chemotherapy that includes cyclophosphamide, carboplatin, or doxorubicin.

Response rates for no nausea or mild nausea were also numerically higher in females treated with granisetron, compared to prochlorperazine, at 48 h. At 72 h, efficacy were comparable for granisetron and prochlorperazine.

Conclusion: Oral granisetron is well tolerated and more effective than prochlorperazine in preventing nausea and vomiting for up to 48 gruben sex following treatment with moderately emetogenic chemotherapy.

Efficacy variables were assessed 48 and 72 h after administration of chemotherapy, and included no emesis, no nausea, no moderate or severe nausea, and no antiemetic rescue. Methods: Prior to chemotherapy, patients were stratified by gender and randomized to receive oral granisetron 1 mg tablet twice daily or prochlorperazine 10 mg sustained release capsule twice daily.

Gruben sex analysis included all patients who received medication.

Antiemetics were administered for seven consecutive days. Study agents were administered 1 h prior to and 12 h after chemotherapy. No-nausea rates at 48 h were numerically higher for all patients combined and females who received granisetron rather than prochlorperazine.